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About Tacrolimus

  • Author:Kathy
  • Source:www.oceanchinachem.com
  • Release on :2016-06-04
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Tacrolimus and FK506, from Streptomyces (Streptomyces tsukubaensis) isolated from the fermentation product, its chemical structure is 23 yuan ring lactone class antibiotic. As a powerful new immunosuppressants, mainly by inhibiting the release of interleukin - 2-2 (L), fully inhibit the role of T cells, a ring of spore (CsA) 100 times stronger. In recent years, as a line of the liver and kidney transplantation medicine, in 14 countries such as Japan, the United States. Clinical trials showed that the heart, lung, intestine, bone marrow transplant in the application has a good curative effect. And FK506 in the treatment of atopic dermatitis (AD), systemic lupus erythematosus (SLE) and autoimmune autoimmune diseases such as eye disease also play an active role.
Liver, heart, kidney and bone marrow transplant patients with immunosuppressive drugs of choice, after transplantation rejection of traditional immunosuppression solution resistance, also can choose the drug. Adverse reactions are similar to those of cyclosporine.