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Clindamycin hydrochloride Notes

  • Author:Hubei Ocean Biotech Co,.LTd
  • Source:www.oceanchinachem.com
  • Release on :2016-04-22
Pregnancy Category C. Pregnant and lactating women, used with caution in patients with severe liver and kidney dysfunction. When taking large amounts of water should be sent to the next. Deep intramuscular injection should be injected. Prohibits direct intravenous injection, can cause the heart to stop breathing.
Clindamycin and lincomycin disabled patients with a history of allergies.
1. Patients may be allergic to lincomycin when clindamycin is also allergenic.
2. Diagnosis of interference: After taking the serum alanine aminotransferase and aspartate aminotransferase may have increased.
3. The following should be careful:
(1) bowel disease or previous history, especially such as ulcerative colitis, enteritis, or antibiotic-associated colitis.
(2) liver dysfunction.
(3) severe renal dysfunction.
(4) In order to prevent the occurrence of acute rheumatic fever, the course of treatment with clindamycin hemolytic streptococcus infection, and at least 10 days.
5. Must pay close attention to the number of stool during treatment, where there is an increase in frequency of bowel movements, pseudomembranous colitis should be noted that the possibility should be promptly discontinued and appropriate treatment.
6. Processing clindamycin-induced pseudomembranous colitis, mild withdrawal is expected to effectively separate, moderate to severe patients need to correct water and electrolyte imbalance. Such as the above treatment, no significant improvement in the disease, should give oral metronidazole 250 ~ 500mg, three times a day. Reusable as relapse when oral metronidazole, could be replaced is still valid when vancomycin (or vancomycin) oral, adult day 0.5 ~ 2.0g, 3 to 4 times daily.
7. Patients with renal dysfunction (except severe impaired outside), without reducing the amount of goods in general. Patients with severe renal and (or) liver dysfunction, when the use of the product subject to the serum drug monitoring.
8. This product can cause even insensitive to the chemicals microbial overgrowth, especially fungi, so the need to pay attention to superinfection occurs applications.

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