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JACC-HF: Name for Aspirin! Heart failure patients can safely take aspirin!

  • Author:Jane
  • Source:YAOZHI
  • Release on :2017-08-04
Many studies are very concerned about the safety of aspirin in the treatment of heart failure, a recent study published in the international magazine JACC: Heart Failure, Columbia University Medical Center (Columbia University Medical Center, CUMC) researchers found Aspirin has some safety in the treatment of heart failure; the researchers in the study of more than 2,300 patients found that taking aspirin every day may not increase the individual due to heart failure and the risk of hospitalization or death.

Of course, the safety of aspirin is a matter of great concern to everyone because, in theory, aspirin interferes with the efficacy of specific drugs for heart failure. Two previous studies have shown that aspirin may increase the risk of heart failure in individuals Risk. In this latest study, the researchers conducted a 10-year follow-up study of patients in 168 study centers in 11 countries, comparing the long-term benefit of aspirin and blood diluent-warfarin use to patients The

"I think the use of aspirin is safe for patients with heart failure," said Shunichi Homma, a researcher. "I think that the adverse effects of aspirin prescription should not be worrisome. We have seen that the use of aspirin is safe for patients with heart failure. Failure, which is a chronic disease, that is, the heart can not effectively pump blood to meet the daily needs of the body, which often lead to patient fatigue, difficulty breathing and limb swelling.

In general, heart attacks or coronary heart disease can cause myocardial damage, which in turn leads to heart failure. In general, these patients will be recommended to use aspirin to reduce the risk of one or more heart attacks, but the problem is that aspirin can interfere with ACE Inhibitors or angiotensin receptor blockers (ARBs), both of which are key drugs for controlling heart failure, which enhance the release of prostaglandins in the blood, whereas aspirin produces the opposite effect The

In the latest study, the researchers assigned participants to take aspirin or warfarin, followed by analysis of the corresponding clinical data. Patients were treated with 352 mg of aspirin daily. After more than 10 years of follow-up study, the researchers found that patients with aspirin 19% of patients were hospitalized or died due to heart failure, and 23% of patients in the warfarin group had the same situation. In addition, the researchers considered other factors, including the age of the patient, heart disease Severity, etc. In the end, they found that there was no statistically significant difference between the two groups in the risk of heart failure complications.

Of course, aspirin is not at risk, it can induce gastrointestinal bleeding, and even cause patients with hemorrhagic shock; so patients should be under the guidance of a doctor medication; at the same time, the researcher Susan Graham put forward another point of view, he believes , In general, heart patients and the elderly at any time will take a lot of prescription drugs, which may reflect the potential interaction between the importance of drug research, and we must be in-depth study to clarify the patient Whether a drug will affect the effect of other drugs, based on the study we found that the administration of aspirin for patients with heart failure is safe.

From:John R. Teerlink, Min Qian, Natalie A. Bello, et al.Aspirin Does Not Increase Heart Failure Events in Heart Failure Patients From the WARCEF Trial. JACC: Heart Failure(2017) DOI: 10.1016/j.jchf.2017.04.011