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Medical Use of Cilnidipine

  • Author:Ray Dean
  • Source:www.oceanchinachem
  • Release on :2016-04-01

As a calcium channel blocker. Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function. 


Dual L-type and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity.Lowers mean blood pressure and reduces the size of cerebral infarction in the rat model of focal brain ischemia.Compared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists.

 

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