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Pharmacological Function Of Carvedilol

  • Author:Ray Dean
  • Source:www.oceanchinachem.com
  • Release on :2016-07-13

Carvedilol belongs vasodilatory β-adrenergic receptor blockers, but both for the β1 or β2 receptor blockade intensity was significantly higher than α1 receptor blockade. Therefore, this product has a moderate and mild vasodilator membrane stabilizing effect, and no intrinsic sympathomimetic activity. In addition, with large doses of calcium antagonism Shihai. Myocardial infarction animal models confirmed that this product has reduced myocardial infarct size, scavenging oxygen free radicals, protecting the role of the heart.

 

This is suitable for hypertension, especially for those with hypertension and ischemic heart disease. Compared with other β-blockers, heart rate and stroke volume index effects are weaker when this product reduced movement. Also used to treat angina, or congestive heart failure. Can improve myocardial oxygen supply / demand ratio of oxygen and reduce cardiac afterload.

 

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