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Pharmacology &Toxicology of Dexamethasone Phosphate Sodium

  • Author:Hubei Ocean Biotech Co,.LTd
  • Source:www.oceanchinachem.com
  • Release on :2016-04-28
Dexamethasone Phosphate Sodium  is adrenocorticotropic hormone drug. Has anti-inflammatory, anti-allergic, anti-rheumatic, immunosuppressive effects, its mechanism of action is:
(1) anti-inflammatory effects: This product is to reduce and prevent tissue response to inflammation, thereby reducing the performance of inflammation. It can inhibit inflammatory cells, including leukocytes and macrophages accumulation at sites of inflammation, and inhibition of phagocytosis, lysosomal enzyme release, and synthesis and release of chemical mediators of inflammation.
(2) immunosuppressive effects: including the prevention or inhibition of cell-mediated immune response, delayed hypersensitivity reactions, reducing the T lymphocytes, monocytes, macrophages acidic number of cells, reduced binding to cell surface immunoglobulin receptor capacity and inhibit the synthesis and release of interleukin, thereby reducing the T lymphocytes to lymphoblastoid cell transformation, and to alleviate the situation of the primary immune response to expansion. This product also reduces the immune reviewed through the basement membrane, and can reduce the concentration of complement components and immunoglobulins.

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