News

Precautions OF Hydrocortisone acetate

  • Author:Hubei Ocean Biotech Co,.LTd
  • Source:www.oceanchinachem.com
  • Release on :2016-06-03

Precautions OF Hydrocortisone acetate


  Long-term large doses of corticosteroid hormone drugs can cause iatrogenic adrenal hyperparathyroidism (category Cushing's syndrome), expressed as moon face, buffalo hump, central obesity, thin skin and purple stripes, muscle weakness and atrophy , osteoporosis, high blood sugar, diabetes, hypertension, hypokalemia, masculine women, such as hairy, bearded, amenorrhea, sound rough, etc. (metabolites with weak androgen role), inhibit growth in children, fetal malformation, evoked the spread of infection, induced ulcer disease, induced psychosis, induced diabetes, hypertension induced induced pancreatitis; withdrawal syndrome (myalgia, muscle stiffness, joint pain, etc.); rebound phenomenon (reduction too fast or sudden withdrawal, the original symptoms may appear quickly or worsening); iatrogenic adrenal hypofunction (adrenal crisis category): long-term high-dose use, due to the negative feedback effects of endogenous glucocorticoid secretion, even adrenal cortical atrophy after the sudden withdrawal, in case of stress conditions, due to the lack of endogenous cortisol secretion can occur adrenal insufficiency syndrome, severe cases can produce similar adrenal crisis, such as hypotension, hypoglycemia, coma, shock, the patient may suddenly collapsed. Hydrocortisone should be timely first aid, first day 300mg, second day 100 ~ 200mg, intravenous infusion, supplemented after rehydration, anti-shock and symptomatic treatment until the condition improves to alternative therapies. Adrenal cortex hyperthyroidism, hypertension, atherosclerosis, edema, glaucoma, congestive heart failure, diabetes, ulcer disease, mental illness, epilepsy, osteoporosis, early pregnancy, postpartum, growing children, trauma, postoperative recovery period, usually a viral infection, bacterial infection and enzyme active tuberculosis patients hanged. Bacterial infections must cooperate with large doses of effective antimicrobial drugs. It should carry salt, low sugar, high protein diet, potassium, calcium and vitamin D. Medication more than two weeks, should gradually decrease slow withdrawal. Injectable ACTH25U / day if necessary.


  HBOcean Biotech Co., Ltd is a leading professional enterprise focus on  pharmaceutical products and APIs, with integrating production and trade for global valued customer with our superior quality and reliable cooperation. Should you have any interest in our products, welcome to take view at our site or contact us for more details.