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Rapamycin: From immunosuppressive drugs into anti-aging medicine

  • Author:Ray Dean
  • Source:www.oceanchinachem
  • Release on :2016-04-13

Rapamycin (RAPA) is a novel macrolide immunosuppressant. Rapamycin through different cytokine receptor blocker signal transduction, blocking T lymphocytes and other cells from G1 to S phase of the process, so as to exert immunosuppressive effects. From a clinical point of view applications, rapamycin has a good anti-rejection effect and with cyclosporine A (CsA) and FK506 and other immunosuppressive agents have good synergy, is an effective, low toxicity, no immunosuppressant nephrotoxicity. A study from the University of Texas showed that rapamycin can be used to treat Alzheimer's disease, the drug ingredient is also present in the soil of Easter Island bacterial secretions

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