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The Effects of Neomycin Sulphate

  • Author:Kathy
  • Source:www.oceanchinachem.com
  • Release on :2016-04-29

    Neomycin sulphate is a kind of aminoglycoside antibiotics. The goods of staphylococcus aureus (methicillin sensitive strains), corynebacterium genus, e. coli, klebsiella bacteria genera, proteus and enterobacteriaceae bacteria have good antibacterial effect, for each group streptococcus, streptococcus pneumoniae, enterococcus is active. This article pseudomonas aeruginosa, oxygen resistance. Bacteria to streptomycin, kanamycin and neomycin, have a partial or total cross resistance between gentamycin. Neomycin systemic medication has significant nephrotoxicity and ototoxicity, is currently limited to oral or topical application.

 

     Drug interactions:

1. Long-term share with oral contraceptives (estrogen) may cause the failure of contraception, and increase the incidence of bleeding.


2. Oral neomycin can affect digitalis glycosides, fluorouracil, methotrexate, penicillin V, the absorption of vitamin A and vitamin B12, make curative effect is reduced; So the patients should be closely observed on the curative effect of digitalis drugs is changing. The patient of oral neomycin share colchicine and vitamin A, vitamin B12 requirements may increase.


3. The goods should not be with other renal toxicity of pooling and ototoxic drugs.


4. Share, and neuromuscular blockers may increase neuromuscular blocking effect, lead to skeletal muscle weakness, etc.

 

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