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What is Cetirizine HCL?

  • Author:Hubei Ocean Biotech Co,.LTd
  • Source:www.oceanchinachem.com
  • Release on :2016-04-15
Cetirizine is a metabolite of hydroxyzine human body, animal experiments show that the West cetirizine hydrochloride as an outer peripheral H1-receptor antagonist, inhibit the transmission and the role of histamine, but also inhibit the participation allergic vasoactive peptide and substance P, reducing the movement of inflammatory cells to effectively suppress allergic skin. This product can significantly reduce airway allergic asthma caused by histamine, reduce allergy caused by a specific allergen. This product has no obvious anticholinergic and anti-serotonin action. In clinical studies found that cetirizine than placebo more common side effect is dry mouth. In vitro receptor binding studies have shown that this product with other H1 receptor affinity and no significant effect. In effective doses, the product easily through the blood-brain barrier, and will not affect the central nervous system and cause side effects.

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