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What is Vitamin E nicotinate

  • Author:Hubei Ocean Biotech Co,.LTd
  • Source:www.oceanchinachem.com
  • Release on :2016-06-12
Pharmacological effects  of Vitamin E nicotinate
Capillary permeability can specifically inhibit kininase hyperthyroidism caused to release bradykinin, lower blood pressure. There strengthen blood vessels, can stabilize the microsomal membranes to prevent hemolysis, prolong the life of red blood cells and inhibiting microsomal membrane damage. Can inhibit cholesterol biosynthesis and deposition in the vessel wall, promoting its excretion in the bile, cholesterol accelerated discharge from the stool. Can inhibit sodium retention and heart edema. Still capable of promoting the biosynthesis of DNA.
Pharmacokinetics of Vitamin E nicotinate 
Oral easily absorbed, in some of the blood is oxidized to quinones α- fertility and partly in the adrenal, ovary, and adipose tissue hydrolysis of vitamin E, which is then metabolized by the liver, a small part of the urinary excretion, most slowly from biliary excretion.
Indications
Useful in the treatment of cerebral arteriosclerosis, stroke, traumatic brain injury sequelae, abnormal lipid metabolism and coronary atherosclerotic heart disease, hypertension, coronary insufficiency and blood circulation disorder caused dizziness, tinnitus, vertigo, numbness, limb rigidity embolism.
Contraindications edit
(Unclear)
Adverse reactions of Vitamin E nicotinate 
Occasional mild dizziness, stomach discomfort, they can still have constipation, diarrhea, stomach pain, loss of appetite, nausea.
Dosage
Each 100 ~ 200mg, 3 times a day after meals.
Drug Interactions
You can reduce the toxicity of poisonous lanatoside and digitalis preparations without reducing the role of the two.
Expert Reviews of Vitamin E nicotinate 
Tocopherol nicotinate is an activator of microcirculation. Which increases brain and peripheral vascular blood circulation effect of vitamin E is relatively good, longer duration of action than niacin. Tocopherol nicotinate still capable of inhibiting cholesterol biosynthesis. In addition, to strengthen the blood vessels. Tocopherol nicotinate direct effect on the vascular wall, peripheral vascular dilation, promote skin blood circulation, increase blood flow lasting effect. Which increases skin circulation was stronger than vitamin E.
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