Anesthetic Agents of Lidocaine

  • Author:Ray Dean
  • Release on :2017-02-17

Lidocaine is a clinical clinical commonly used local anesthetic, is the prevention and treatment of acute myocardial infarction and a variety of heart disease complicated with rapid ventricular arrhythmia drugs, acute myocardial infarction ventricular premature beats, ventricular tachycardia and ventricular tremor of choice medicine.


This product is amide local anesthetic. Blood absorption or intravenous administration of the central nervous system has obvious excitement and inhibition of biphasic effects, and no excitement of excitement, blood concentration is low, the emergence of analgesic and lethargy, pain threshold increased; with the dose plus Large, role or toxicity increased, sub-poisoning plasma concentration when the anticonvulsant effect; when the plasma concentration of more than 5mg · ml-1 can occur convulsions. This product at low doses, can promote cardiomyocyte K + outflow, reduce myocardial autonomy, and has anti-ventricular arrhythmia; in the treatment dose, the cardiomyocyte electrical activity, atrioventricular conduction and myocardial contraction Significantly affected; further increase in plasma concentration, can cause slow heart rate, atrioventricular block, inhibition of myocardial contractility and cardiac output decreased.


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