Biochemical Effects of Lactic Acid

  • Author:Ray Dean
  • Release on :2016-06-14

Lactic acid (IUPAC name: 2-hydroxy acid) is a compound that plays a role in many biochemical processes. It is a carboxylic acid, the formula is C3H6O3. It is a carboxylic acid containing a hydroxyl group, it is a α- hydroxy acids (AHA). In an aqueous solution of its carboxyl release a proton, which produce lactic acid ion CH3CHOHCOO-


During fermentation lactic dehydrogenase pyruvate is converted to L-lactic acid. Lactic acid is produced continuously in the general metabolism and movement, but its concentration is generally not rise. Only in lactate production process accelerated when lactic acid can not be transported in a timely manner will improve their concentration. Lactate transport speed by a series of factors, including the oxidation of monocarboxylic transporters, concentration and isomeric forms of lactate dehydrogenase, organization. Generally the concentration of lactate in the blood is not moving at the time of 1-2mmol / L, when a strong movement can be increased to 20mmol / L.


In general case when the energy of the organization can not be met through aerobic respiration, tissue does not get enough oxygen or oxygen can not be fast enough to handle the lactic acid concentration will rise. In this case not be timely pyruvate dehydrogenase converting pyruvate to acetyl coenzyme A, began to accumulate pyruvate. In this case, if not lactate dehydrogenase reducing pyruvate to lactate, then the process of glycolysis and ATP synthesis will be inhibited. Process for producing lactic acid: pyruvate + NADH + H + lactate + NAD ++ 2H


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