Clinical Application of Cimetidine

  • Author:Ray Dean
  • Release on :2016-07-29

Cimetidine is white or white crystalline powder, bitter taste. Soluble in methanol, dissolved in ethanol, slightly soluble in isopropanol, slightly soluble in water, soluble in dilute hydrochloric acid. Significant inhibition of gastric acid secretion, can significantly inhibit basal and nocturnal gastric acid secretion, can inhibit gastric acid secretion by histamine, pentagastrin points, insulin and food stimulation, and it reduces acidity, due to a chemical stimulus erosive gastritis caused by the prevention and protection of stress ulcer and upper gastrointestinal bleeding have significant effect. For the treatment of duodenal ulcer, gastric ulcer, upper gastrointestinal bleeding, chronic colitis, herpes zoster, chronic urticaria embolism. Antiviral and immune enhancement to a certain extent.


Cimetidine has a non-steroidal anti-androgen-like effect is dihydrotestosterone (DHT) competitive inhibitor,Enable DHT plasma concentration decreases, it can be for the treatment of male hormones increase the diversity of the disease. Someone with cimetidine 0.4 g, day 1, treatment of benign prostatic hyperplasia, in the short term so that normal urination. Abroad there have been using this acne treatment in 45 cases, 95.5% efficiency; the FDA to treat female hirsutism, but also allows rapid hair growth slows.


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