Medical Action of Cefotaxime Sodium

  • Author:Ray Dean
  • Source:www.oceanchinachem,com
  • Release on :2016-06-11

Cefotaxime Sodium is a white, off-white or yellowish white crystals; odorless or slight special smell. This product is soluble in water, slightly soluble in ethanol, insoluble in chloroform. Specific rotation to take this product, accurately weighed, dissolved in water and diluted into a solution containing 10mg per 1ml of determination according to the law, the specific rotation of +56 degrees to +64 degrees. Absorption coefficient of this product, accurately weighed, add 0.01mol / L hydrochloric acid dissolved and diluted per 1ml containing about 10μg solution, according to spectrophotometric determination of absorbance at the wavelength of 262nm, calculated on the anhydrous absorption coefficient of 400 to 440.


This product is the third generation semi-synthetic cephalosporin antibacterial spectrum than cefuroxime wider action against Gram-negative bacteria stronger antimicrobial spectrum, including Haemophilus influenzae, Escherichia coli, Salmonella Klebsiella aerogenes metals and Proteus mirabilis, Neisseria, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus. Patients are susceptible to various infections, such as respiratory, facial, abdominal, biliary tract, meningitis, gonorrhea, urinary tract infections, septicemia.


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