Medical Effects of Bupropion Hydrochloride

  • Author:Ray Dean
  • Source:www.oceanchinachem,com
  • Release on :2016-06-10

Bupropion Hydrochloride is a cytochrome P450B6 Drug Metabolism: In vitro tests showed that bupropion is primarily metabolized by the cytochrome P450B6 isozymes, so the presence of potential interactions with other cytochrome P450B6 isoenzyme drugs.


MAO inhibitors: Animal studies have shown that monoamine oxidase inhibitor (MAOI) phenelzine bupropion may be increased acute toxicity.


Levodopa: Clinical data show that while the use of amphetamine He ketone and levodopa, may increase the incidence of adverse reactions. Patients taking levodopa should be careful while using this service, start using the smallest dose and then gradually increase the amount.


Lower the seizure threshold drugs: the goods and lower the seizure threshold, drugs (such as: antipsychotics, antidepressants, theophylline, systemic steroids, etc.) or treatment (such as a sudden interruption of the benzodiazepine class of drugs) together should use extreme caution.


Nicotine transdermal patches: Clinical studies suggest that bupropion sustained-release tablets and nicotine transdermal patch in combination with a high incidence of hypertension emergency treatment, so the combination of the two blood pressure should be closely monitored.


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