Medical Effects of Rocuronium Bromide

  • Author:Ray Dean
  • Source:www.oceanchinachem
  • Release on :2016-05-12

Rocuronium Bromide, a non-depolarizing neuromuscular blocking agents, vecuronium and pancuronium structurally similar. And other non-depolarizing drugs, it is competing with the cholinergic synapses of motor nerve terminals receptor binding, antagonism to acetylcholine.


Non-depolarizing neuromuscular blocking agent succinylcholine than security, but the slow onset, long duration of action, there is a disadvantage in some applications. Rocuronium rapid onset of action and dose-dependent manner. In the non-depolarizing neuromuscular blocking agents, the product is the fastest onset, usually in 60 seconds after intravenous cannula will be able to provide excellent conditions.


The product inhibition of motor nerve terminal chlorine than d- tubocurarine and pancuronium bromide weak, but with vecuronium similar. Intravenous anesthetics does not affect the neuromuscular blocking effect of this product, when the action does not affect the process.


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