Pharmaceutical Raw Material of Cefuroxime Sodium

  • Author:Ray Dean
  • Source:www.oceanchinachem,com
  • Release on :2016-06-11

Cefuroxime Sodium is suitable for the treatment of infections caused by susceptible bacteria. - Lower respiratory tract infections: such as acute bronchitis and acute exacerbation of chronic bronchitis and pneumonia. - Upper respiratory tract infections: including ear, nose and throat infections such as otitis media, sinusitis, tonsillitis and pharyngitis. - Genitourinary tract infections: such as pyelonephritis, cystitis and urethritis. Cefuroxime is also available for parenteral dosage forms of sodium. In clinical need injection to oral administration, you can use the same sequential antibiotic therapy.


After oral administration, cefuroxime axetil is absorbed in the gastrointestinal tract and rapidly hydrolyzed in the intestinal mucosa and blood to release cefuroxime into the circulation. After the meal taking the product can get the best absorption. After oral administration of the goods 2-3 hours up to the peak plasma concentration of cefuroxime. Serum half-life of about 1.2 hours. Approximately 50% of the protein-bound form of cefuroxime. Cefuroxime is not metabolized by glomerular filtration and tubular secretion form is excreted. Combined with probenecid, would mean serum concentration of the drug - the area under the curve increased by 50%.


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