Pharmacological Effects of Capecitabine

  • Author:Ray Dean
  • Source:www.oceanchinachem,com
  • Release on :2016-06-11

Capecitabine is a kind that can be converted in vivo to 5-FU antimetabolite fluoropyrimidine carbamate deoxynucleoside drug developed by Roche, trade name Xeloda, capable of inhibiting cell division and interfere with RNA and proteins (protein) synthesis. Suitable for further treatment including paclitaxel and anthracycline chemotherapy ineffective advanced primary or metastatic breast cancer. Mainly used for advanced primary or metastatic breast cancer, colorectal cancer, colon cancer, and treatment of gastric cancer.


Capecitabine is an inhibitor of the bone marrow, it is necessary each medication before blood tests to monitor blood cell and platelet counts. This product has liver toxicity, so the liver function should be checked regularly. Also, cardiac function should be monitored to avoid irreversible toxicity. For intravenous administration, it should be analyzed before treatment is suitable for the above-described organ function.


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