Pharmacological Effects of Chondroitin Sulfate

  • Author:Kathy
  • Release on :2016-06-21

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   Chondroitin Sulfate is widely exist in human and animal cartilage. The main medicinal preparation contains chondroitin sulfate A and chondroitin sulfate C two isomers, different breed, age and so on different content of chondroitin sulfate in animal cartilage. Its pharmacological effects are:


  1. CS can remove the lipid and lipoprotein in the blood in the body, remove blood vessels around the heart of cholesterol, prevention and treatment of atherosclerosis, and increase lipid and fatty acids in cell conversion rate.


   2. CS can effectively prevent coronary heart disease. On experimental atherosclerosis model has resistance to atherosclerosis and resistance on atheromatous plaque formation; Increase of atherosclerosis, coronary artery points or collateral circulation, and can accelerate the experimental coronary atherosclerosis or embolism caused by degeneration of myocardial necrosis or healing, regeneration and repair.


   3. Can increase cell messenger RNA (mRNA) and deoxyribonucleic acid (DNA) biosynthesis and promote the role of cell metabolism.


   4. Low anticoagulant activity. Chondroitin sulfate have moderate anticoagulant effect, each LMG chondroitin sulfate is equivalent to A 0.45 U heparin anticoagulant activity. The anticoagulant activity does not depend on antithrombin III and play a role, it can play by fibrinogen system anticoagulant activity.


   5. Chondroitin sulfate also has anti-inflammatory, accelerate wound healing and antitumor effect.