Pharmacological Effects of Clarithromycin

  • Author:Ray Dean
  • Release on :2016-08-08

Clarithromycin erythromycin derivatives. Antibacterial spectrum and erythromycin, roxithromycin same, but against Gram-positive bacteria such as Streptococcus pneumoniae, Staphylococcus slightly better antibacterial effect, and erythromycin resistant strains also induced a certain antibacterial activity. Clarithromycin and its antibacterial effect against Haemophilus influenzae enhanced metabolites in the body. The product of Neisseria gonorrhoeae, Li Si te bacteria, Campylobacter jejuni also have a role, and the role of Legionella pneumophila, Mycoplasma pneumoniae, Chlamydia trachomatis, Ureaplasma urealyticum and other than erythromycin strong in recent years, the development of new the role of the more prominent species.


The drug for gram-positive bacteria such as Staphylococcus aureus, Streptococcus pneumoniae bacteria, which inhibit some Gram-negative bacteria such as Haemophilus influenzae, Bordetella pertussis, gonorrhea, Legionella pneumophila and some anaerobic bacteria such as Bacteroides fragilis, digestion Streptococcus, Propionibacterium acnes also inhibit. In addition to Mycoplasma also inhibited. The drug is characterized by in vitro antibacterial activity of erythromycin similar, but in some bacteria such as Staphylococcus aureus, Streptococcus, Haemophilus influenzae and strong antibacterial activity than erythromycin. And erythromycin between cross-resistance.


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