Pharmacology &Toxicology of Dexamethasone Acetate

  • Author:Hubei Ocean Biotech Co,.LTd
  • Release on :2016-04-25
Dexamethasone acetate is a drug, adrenal cortical hormone drugs. White or almost white crystal or crystalline powder; odorless, slightly bitter taste. Soluble in acetone, methanol or ethanol and dissolved in ethanol or chloroform, slightly soluble, very slightly soluble in ether, insoluble in water.
Loose sheet
Adrenocorticotropic hormone drugs, anti-inflammatory, anti-allergic, anti-shock effect is more significant than prednisone, and potassium sodium retention and promoting the removal of very light on the pituitary - adrenal strong inhibition.
1, anti-inflammatory effects: This product can reduce and prevent tissue response to inflammation, thereby reducing inflammation of the performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation at sites of inflammation, and inhibition of phagocytosis, lysosomal enzyme release, and synthesis and release of chemical mediators of inflammation. You can reduce and prevent tissue response to inflammation, thereby reducing the performance of inflammation.
2, immunosuppressive effects: including the prevention or inhibition of cell-mediated immune response, delayed hypersensitivity reactions, reducing the T lymphocytes, monocytes, eosinophils number, reducing the binding capacity of immunoglobulin with cell surface receptors and inhibit the synthesis and release of interleukin, thereby reducing the T lymphocytes to lymphoblastoid cell transformation, and reduce the primary immune response to expansion. Reduces immune complexes through the basement membrane, and can reduce the concentration of complement components and immunoglobulins.
Adrenocorticotropic hormone drugs. This product has anti-inflammatory, anti-allergic effects, can inhibit the proliferation of connective tissue and reduce the permeability of the capillary wall and cell membrane, reducing the amount of inflammatory exudate inhibit the formation and release of histamine and other toxic substances.

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