What is Entecavir

  • Author:Hubei Ocean Biotech Co,.LTd
  • Release on :2016-05-10
Entecavir for antiviral nucleoside reverse transcriptase inhibitors, the drug can inhibit the replication of hepatitis B virus and quantity. Three step HBV replication, comprising: a base to start; genome (mRNA) reverse replication; and deoxyribonucleic acid (DNA) synthesis can be inhibited by entecavir. This product is suitable for active viral replication, persistently elevated serum transaminases ALT or liver histology showed chronic active lesions of adult hepatitis B treatment.

In the clinical trials entecavir five years we have not been found because of adverse reactions require discontinuation of cases occur. But in some special patients, such as severe hepatitis must be used with caution, because there may be lactic acidosis, In addition, entecavir animal studies, has been found in lung tumors in experimental animals than normal doses of more than 4 times , carcinogenicity increase, but people who have not found carcinogenic phenomenon, for which the FDA 10-year carcinogenicity studies in progress.

After taking the drug need to use before and two hours of use on an empty stomach, so as not to affect its efficacy.

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